Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4(+) T cell loss is associated with double-negative T cells

SIV infection of natural host species such as sooty mangabeys results in high viral replication without clinical signs of simian AIDS. Studying such infections is useful for identifying immunologic parameters that lead to AIDS in HIV-infected patients. Here we have demonstrated that acute, SIV-induc...

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主要な著者: Milush, Jeffrey M., Mir, Kiran D., Sundaravaradan, Vasudha, Gordon, Shari N., Engram, Jessica, Cano, Christopher A., Reeves, Jacqueline D., Anton, Elizabeth, O’Neill, Eduardo, Butler, Eboneé, Hancock, Kathy, Cole, Kelly S., Brenchley, Jason M., Else, James G., Silvestri, Guido, Sodora, Donald L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049370/
https://ncbi.nlm.nih.gov/pubmed/21317533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44876
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