Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4(+) T cell loss is associated with double-negative T cells

SIV infection of natural host species such as sooty mangabeys results in high viral replication without clinical signs of simian AIDS. Studying such infections is useful for identifying immunologic parameters that lead to AIDS in HIV-infected patients. Here we have demonstrated that acute, SIV-induc...

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Autors principals: Milush, Jeffrey M., Mir, Kiran D., Sundaravaradan, Vasudha, Gordon, Shari N., Engram, Jessica, Cano, Christopher A., Reeves, Jacqueline D., Anton, Elizabeth, O’Neill, Eduardo, Butler, Eboneé, Hancock, Kathy, Cole, Kelly S., Brenchley, Jason M., Else, James G., Silvestri, Guido, Sodora, Donald L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049370/
https://ncbi.nlm.nih.gov/pubmed/21317533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44876
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