An ATM/Chk2-mediated DNA damage responsive signaling pathway suppresses Epstein-Barr virus transformation of primary human B cells

Epstein-Barr virus (EBV), an oncogenic herpesvirus that causes human malignancies, infects and immortalizes primary human B cells in vitro into indefinitely proliferating lymphoblastoid cell lines, which represent a model for EBV-induced tumorigenesis. The immortalization efficiency is very low sugg...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Nikitin, Pavel A., Yan, Christopher M., Forte, Eleonora, Bocedi, Alessio, Tourigny, Jason P., White, Robert E., Allday, Martin J., Patel, Amee, Dave, Sandeep S., Kim, William, Hu, Katherine, Guo, Jing, Tainter, David, Rusyn, Elena, Luftig, Micah A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049316/
https://ncbi.nlm.nih.gov/pubmed/21147465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.11.004
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items