EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

Polycomb protein group (PcG)-dependent trimethylation on H3K27 (H3K27me3) regulates identity of embryonic stem cells (ESCs). How H3K27me3 governs adult SCs and tissue development is unclear. Here, we conditionally target H3K27 methyltransferases Ezh2 and Ezh1 to address their roles in mouse skin hom...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ezhkova, Elena, Lien, Wen-Hui, Stokes, Nicole, Pasolli, H. Amalia, Silva, Jose M., Fuchs, Elaine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2011
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049289/
https://ncbi.nlm.nih.gov/pubmed/21317239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2019811
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