L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1

Glioblastomas (GBMs) are highly lethal brain tumours with current therapies limited to palliation due to therapeutic resistance. We previously demonstrated that GBM stem cells (GSCs) display a preferential activation of DNA damage checkpoint and are relatively resistant to radiation. However, the mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Lin, Wu, Qiulian, Huang, Zhi, Guryanova, Olga A, Huang, Qian, Shou, Weinian, Rich, Jeremy N, Bao, Shideng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049209/
https://ncbi.nlm.nih.gov/pubmed/21297581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.10
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