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L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1
Glioblastomas (GBMs) are highly lethal brain tumours with current therapies limited to palliation due to therapeutic resistance. We previously demonstrated that GBM stem cells (GSCs) display a preferential activation of DNA damage checkpoint and are relatively resistant to radiation. However, the mo...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049209/ https://ncbi.nlm.nih.gov/pubmed/21297581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.10 |
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