L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1

Glioblastomas (GBMs) are highly lethal brain tumours with current therapies limited to palliation due to therapeutic resistance. We previously demonstrated that GBM stem cells (GSCs) display a preferential activation of DNA damage checkpoint and are relatively resistant to radiation. However, the mo...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Lin, Wu, Qiulian, Huang, Zhi, Guryanova, Olga A, Huang, Qian, Shou, Weinian, Rich, Jeremy N, Bao, Shideng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049209/
https://ncbi.nlm.nih.gov/pubmed/21297581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.10
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