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L1CAM regulates DNA damage checkpoint response of glioblastoma stem cells through NBS1

Glioblastomas (GBMs) are highly lethal brain tumours with current therapies limited to palliation due to therapeutic resistance. We previously demonstrated that GBM stem cells (GSCs) display a preferential activation of DNA damage checkpoint and are relatively resistant to radiation. However, the mo...

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Sonraí Bibleagrafaíochta
Main Authors: Cheng, Lin, Wu, Qiulian, Huang, Zhi, Guryanova, Olga A, Huang, Qian, Shou, Weinian, Rich, Jeremy N, Bao, Shideng
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049209/
https://ncbi.nlm.nih.gov/pubmed/21297581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.10
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