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Caspase-8 as a Therapeutic Target in Cancer
Caspase-8 is an apical caspase which initiates programmed cell death following death receptor ligation. This central role in apoptosis has prompted significant clinical interest in regulating caspase-8 expression and proteolytic activity. However, caspase-8 has also been found to play a number of no...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049203/ https://ncbi.nlm.nih.gov/pubmed/20817393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.07.022 |
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