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The ADP receptor P2Y(1 )is necessary for normal thermal sensitivity in cutaneous polymodal nociceptors

BACKGROUND: P2Y(1 )is a member of the P2Y family of G protein-coupled nucleotide receptors expressed in peripheral sensory neurons. Using ratiometric calcium imaging of isolated dorsal root ganglion neurons, we found that the majority of neurons responding to adenosine diphosphate, the preferred end...

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Autori principali: Molliver, Derek C, Rau, Kristofer K, McIlwrath, Sabrina L, Jankowski, Michael P, Koerber, H Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049184/
https://ncbi.nlm.nih.gov/pubmed/21310055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-13
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