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Helical Hairpin Structure of Influenza Hemagglutinin Fusion Peptide Stabilized by Charge-Dipole Interactions between the N-terminal Amino Group and the Second Helix

The fusion domain of the influenza coat protein hemagglutinin HA2, bound to dodecyl phosphocholine (DPC) micelles, was recently shown to adopt a structure consisting of two anti-parallel α-helices, packed together in an exceptionally tight hairpin configuration. Four interhelical H(α) to C=O aliphat...

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Detalhes bibliográficos
Main Authors: Lorieau, Justin L., Louis, John M., Bax, Ad
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048900/
https://ncbi.nlm.nih.gov/pubmed/21319795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1099775
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