Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

Kindlin-2 is a FERM and PH domain-containing integrin-binding protein that is emerging as an important regulator of integrin activation. How kindlin-2 functions in integrin activation, however, is not known. We report here that kindlin-2 interacts with multiple phosphoinositides, preferentially with...

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Autori principali: Qu, Hong, Tu, Yizeng, Shi, Xiaohua, Larjava, Hannu, Saleem, Moin A., Shattil, Sanford J., Fukuda, Koichi, Qin, Jun, Kretzler, Matthias, Wu, Chuanyue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2011
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048888/
https://ncbi.nlm.nih.gov/pubmed/21325030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.076976
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