Knockdown of Cyclin-dependent Kinase Inhibitors Induces Cardiomyocyte Re-entry in the Cell Cycle

Proliferation of mammalian cardiomyocytes stops rapidly after birth and injured hearts do not regenerate adequately. High cyclin-dependent kinase inhibitor (CKI) levels have been observed in cardiomyocytes, but their role in maintaining cardiomyocytes in a post-mitotic state is still unknown. In thi...

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Bibliographische Detailangaben
Hauptverfasser: Di Stefano, Valeria, Giacca, Mauro, Capogrossi, Maurizio C., Crescenzi, Marco, Martelli, Fabio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048746/
https://ncbi.nlm.nih.gov/pubmed/21209082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.184549
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