Reconstitution of Proapoptotic BAK Function in Liposomes Reveals a Dual Role for Mitochondrial Lipids in the BAK-driven Membrane Permeabilization Process

BAK is a key effector of mitochondrial outer membrane permeabilization (MOMP) whose molecular mechanism of action remains to be fully dissected in intact cells, mainly due to the inherent complexity of the intracellular apoptotic machinery. Here we show that the core features of the BAK-driven MOMP...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Landeta, Olatz, Landajuela, Ane, Gil, David, Taneva, Stefka, DiPrimo, Carmelo, Sot, Begoña, Valle, Mikel, Frolov, Vadim A., Basañez, Gorka
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048708/
https://ncbi.nlm.nih.gov/pubmed/21196599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165852
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia