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Positive Regulatory Domain I (PRDM1) and IRF8/PU.1 Counter-regulate MHC Class II Transactivator (CIITA) Expression during Dendritic Cell Maturation

Dendritic cells (DCs) are key mediators of immune function through robust and tightly regulated presentation of antigen in the context of the MHC Class II. MHC Class II expression is controlled by the transactivator CIITA. CIITA expression in conventional DCs is uniquely dependent on an uncharacteri...

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מידע ביבליוגרפי
Main Authors: Smith, Matthew A., Wright, Gabriela, Wu, Jian, Tailor, Prafullakumar, Ozato, Keiko, Chen, Xianghong, Wei, Sheng, Piskurich, Janet F., Ting, Jenny P.-Y., Wright, Kenneth L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048676/
https://ncbi.nlm.nih.gov/pubmed/21216962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165431
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