Positive Regulatory Domain I (PRDM1) and IRF8/PU.1 Counter-regulate MHC Class II Transactivator (CIITA) Expression during Dendritic Cell Maturation

Dendritic cells (DCs) are key mediators of immune function through robust and tightly regulated presentation of antigen in the context of the MHC Class II. MHC Class II expression is controlled by the transactivator CIITA. CIITA expression in conventional DCs is uniquely dependent on an uncharacteri...

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Detalhes bibliográficos
Main Authors: Smith, Matthew A., Wright, Gabriela, Wu, Jian, Tailor, Prafullakumar, Ozato, Keiko, Chen, Xianghong, Wei, Sheng, Piskurich, Janet F., Ting, Jenny P.-Y., Wright, Kenneth L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048676/
https://ncbi.nlm.nih.gov/pubmed/21216962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.165431
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