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Familial haemophagocytic lymphohistiocytosis: advances in the genetic basis, diagnosis and management
Familial haemophagocytic lymphohistiocytosis (FHL) is a rare autosomal recessive disorder of immune dysregulation associated with uncontrolled T cell and macrophage activation and hypercytokinaemia. The incidence of FHL is 0·12/100·000 children born per year, with a male to female ratio of 1:1. The...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048610/ https://ncbi.nlm.nih.gov/pubmed/21303357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2010.04302.x |
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