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H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

BACKGROUND: Outbreaks of avian influenza (AI) caused by infection with low pathogenic H9N2 viruses have occurred in poultry, resulting in serious economic losses in Asia and the Middle East. It has been difficult to eradicate the H9N2 virus because of its low pathogenicity, frequently causing in app...

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Detalhes bibliográficos
Main Authors: Soda, Kosuke, Asakura, Shingo, Okamatsu, Masatoshi, Sakoda, Yoshihiro, kida, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048564/
https://ncbi.nlm.nih.gov/pubmed/21310053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-64
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