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H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

BACKGROUND: Outbreaks of avian influenza (AI) caused by infection with low pathogenic H9N2 viruses have occurred in poultry, resulting in serious economic losses in Asia and the Middle East. It has been difficult to eradicate the H9N2 virus because of its low pathogenicity, frequently causing in app...

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Bibliografski detalji
Glavni autori: Soda, Kosuke, Asakura, Shingo, Okamatsu, Masatoshi, Sakoda, Yoshihiro, kida, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048564/
https://ncbi.nlm.nih.gov/pubmed/21310053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-64
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