H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens

BACKGROUND: Outbreaks of avian influenza (AI) caused by infection with low pathogenic H9N2 viruses have occurred in poultry, resulting in serious economic losses in Asia and the Middle East. It has been difficult to eradicate the H9N2 virus because of its low pathogenicity, frequently causing in app...

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Hlavní autoři: Soda, Kosuke, Asakura, Shingo, Okamatsu, Masatoshi, Sakoda, Yoshihiro, kida, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048564/
https://ncbi.nlm.nih.gov/pubmed/21310053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-8-64
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