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Counting peptide-water hydrogen bonds in unfolded proteins

It is often assumed that the peptide backbone forms a substantial number of additional hydrogen bonds when a protein unfolds. We challenge that assumption in this article. Early surveys of hydrogen bonding in proteins of known structure typically found that most, but not all, backbone polar groups a...

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Bibliographic Details
Main Authors: Gong, Haipeng, Porter, Lauren L, Rose, George D
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048426/
https://ncbi.nlm.nih.gov/pubmed/21280132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.574
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