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Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide

The human major histocompatibility complex class I antigen HLA-B*2705 binds several sequence-related peptides (pVIPR, RRKWRRWHL; pLPM2, RRRWRRLTV; pGR, RRRWHRWRL). Cross-reactivity of cytotoxic T cells (CTL) against these HLA-B*2705:peptide complexes seemed to depend on a particular peptide conforma...

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Détails bibliographiques
Auteurs principaux: Loll, Bernhard, Rückert, Christine, Hee, Chee Seng, Saenger, Wolfram, Uchanska-Ziegler, Barbara, Ziegler, Andreas
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048413/
https://ncbi.nlm.nih.gov/pubmed/21280120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.559
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