Sensitivity of MRI Tumor Biomarkers to VEGFR Inhibitor Therapy in an Orthotopic Mouse Glioma Model

MRI biomarkers of tumor edema, vascular permeability, blood volume, and average vessel caliber are increasingly being employed to assess the efficacy of tumor therapies. However, the dependence of these biomarkers on a number of physiological factors can compromise their sensitivity and complicate t...

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Detalhes bibliográficos
Main Authors: Farrar, Christian T., Kamoun, Walid S., Ley, Carsten D., Kim, Young R., Catana, Ciprian, Kwon, Seon J., Rosen, Bruce R., Jain, Rakesh K., Sorensen, A. Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048404/
https://ncbi.nlm.nih.gov/pubmed/21390238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017228
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