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Murine Melanoma-Infiltrating Dendritic Cells Are Defective in Antigen Presenting Function Regardless of the Presence of CD4(+)CD25(+) Regulatory T Cells
Tumor-infiltrating dendritic cells are often ineffective at presenting tumor-derived antigen in vivo, a defect usually ascribed to the suppressive tumor environment. We investigated the effects of depleting CD4(+)CD25(+) “natural” regulatory T cells (Treg) on the frequency, phenotype and function of...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048402/ https://ncbi.nlm.nih.gov/pubmed/21390236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017515 |
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