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Nucleotide Binding Switches the Information Flow in Ras GTPases

The Ras superfamily comprises many guanine nucleotide-binding proteins (G proteins) that are essential to intracellular signal transduction. The guanine nucleotide-dependent intrinsic flexibility patterns of five G proteins were investigated in atomic detail through Molecular Dynamics simulations of...

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Bibliografiset tiedot
Päätekijät: Raimondi, Francesco, Portella, Guillem, Orozco, Modesto, Fanelli, Francesca
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048383/
https://ncbi.nlm.nih.gov/pubmed/21390270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001098
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