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Generation of Functional Neutrophils from a Mouse Model of X-Linked Chronic Granulomatous Disorder Using Induced Pluripotent Stem Cells

Murine models of human genetic disorders provide a valuable tool for investigating the scope for application of induced pluripotent stem cells (iPSC). Here we present a proof-of-concept study to demonstrate generation of iPSC from a mouse model of X-linked chronic granulomatous disease (X-CGD), and...

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Detalhes bibliográficos
Main Authors: Mukherjee, Sayandip, Santilli, Giorgia, Blundell, Michael P., Navarro, Susana, Bueren, Juan A., Thrasher, Adrian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048300/
https://ncbi.nlm.nih.gov/pubmed/21408614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017565
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