Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases

Chronic granulomatous disease (CGD) is an inherited orphan disorder caused by mutations in one of the five genes encoding reduced nicotinamide-adenine-dinucleotide-phosphate oxidase subunits, which subsequently lead to impairment in the production of microbicidal reactive oxygen species (ROS). In or...

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Detalhes bibliográficos
Publicado no:Biores Open Access
Main Authors: Brault, Julie, Goutagny, Erwan, Telugu, Narasimha, Shao, Kaifeng, Baquié, Mathurin, Satre, Véronique, Coutton, Charles, Grunwald, Didier, Brion, Jean-Paul, Barlogis, Vincent, Stephan, Jean-Louis, Plantaz, Dominique, Hescheler, Jürgen, Krause, Karl-Heinz, Šarić, Tomo, Stasia, Marie José
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245876/
https://ncbi.nlm.nih.gov/pubmed/25469316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/biores.2014.0045
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