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Insulin stimulates phosphorylation of a 120-kDa glycoprotein substrate (pp120) for the receptor-associated protein kinase in intact H-35 hepatoma cells.

The insulin receptor possesses protein kinase activity, which may play a role in mediating insulin action. Recently, we have identified a glycoprotein (pp120) in rat liver plasma membranes that is phosphorylated by the solubilized insulin receptor in a cell-free system. We now report that insulin st...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Perrotti, N, Accili, D, Marcus-Samuels, B, Rees-Jones, R W, Taylor, S I
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1987
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.10.3137
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