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Dynamics of the folded and unfolded villin headpiece (HP35) measured with ultrafast 2D IR vibrational echo spectroscopy

A series of two-dimensional infrared vibrational echo experiments performed on nitrile-labeled villin headpiece [HP35-(CN)(2)] is described. HP35 is a small peptide composed of three alpha helices in the folded configuration. The dynamics of the folded HP35-(CN)(2) are compared to that of the guanid...

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Autori principali: Chung, Jean K., Thielges, Megan C., Fayer, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048147/
https://ncbi.nlm.nih.gov/pubmed/21321226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100587108
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