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Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes
TAp63, but not its homolog p53, eliminates oocytes that suffered DNA damage. An equivalent gene for guarding the male germ line is currently not known. Here we identify hitherto unknown human p63 transcripts with unique 5′-ends derived from incorporated exons upstream of the currently mapped TP63 ge...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048127/ https://ncbi.nlm.nih.gov/pubmed/21300884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016201108 |
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