Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

Phagocytosed Borrelia burgdorferi (Bb) induces inflammatory signals that differ both quantitatively and qualitatively from those generated by spirochetal lipoproteins interacting with Toll-like receptor (TLR) 1/2 on the surface of human monocytes. Of particular significance, and in contrast to lipop...

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מידע ביבליוגרפי
Main Authors: Cervantes, Jorge L., Dunham-Ems, Star M., La Vake, Carson J., Petzke, Mary M., Sahay, Bikash, Sellati, Timothy J., Radolf, Justin D., Salazar, Juan C.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048123/
https://ncbi.nlm.nih.gov/pubmed/21321205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013776108
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