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Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation

Primary tumors secrete factors that alter the microenvironment of distant organs, rendering those organs as fertile soil for subsequent metastatic cancer cell colonization. Although the lungs are exposed to these factors ubiquitously, lung metastases usually develop as a series of discrete lesions....

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Bibliografski detalji
Glavni autori: Hiratsuka, Sachie, Goel, Shom, Kamoun, Walid S., Maru, Yoshiro, Fukumura, Dai, Duda, Dan G., Jain, Rakesh K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048115/
https://ncbi.nlm.nih.gov/pubmed/21321210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100446108
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