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X-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides

We have determined the X-ray crystal structures of the pre- and postcatalytic forms of the initiation complex of bacteriophage N4 RNA polymerase that provide the complete set of atomic images depicting the process of transcript initiation by a single-subunit RNA polymerase. As observed during T7 RNA...

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Détails bibliographiques
Auteurs principaux: Gleghorn, Michael L., Davydova, Elena K., Basu, Ritwika, Rothman-Denes, Lucia B., Murakami, Katsuhiko S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048110/
https://ncbi.nlm.nih.gov/pubmed/21321236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016691108
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