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Transgenic elimination of high-affinity antidepressant and cocaine sensitivity in the presynaptic serotonin transporter

Serotonin [i.e., 5-hydroxytryptamine (5-HT)]–targeted antidepressants are in wide use for the treatment of mood disorders, although many patients do not show a response or experience unpleasant side effects. Psychostimulants, such as cocaine and 3,4-methylenedioxymethamphetamine (i.e., “ecstasy”), a...

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Hlavní autoři: Thompson, Brent J., Jessen, Tammy, Henry, L. K., Field, Julie R., Gamble, Karen L., Gresch, Paul J., Carneiro, Ana M., Horton, Rebecca E., Chisnell, Peter J., Belova, Yekaterina, McMahon, Douglas G., Daws, Lynette C., Blakely, Randy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048100/
https://ncbi.nlm.nih.gov/pubmed/21282638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011920108
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