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Substrate-specific regulation of ubiquitination by the anaphase-promoting complex

By orchestrating the sequential degradation of a large number of cell cycle regulators, the ubiquitin ligase anaphase-promoting complex (APC/C) is essential for proliferation in all eukaryotes. The correct timing of APC/C-dependent substrate degradation, a critical feature of progression through mit...

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Bibliographic Details
Main Authors: Song, Ling, Rape, Michael
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048074/
https://ncbi.nlm.nih.gov/pubmed/21191176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.1.14387
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