Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo

Although many breast cancers respond to chemotherapy or hormonal therapy, lack of tumor eradication is a central clinical problem preceding the development of drug-resistant tumors. Using the K14cre;Brca1(F5–13/F5–13);p53(F2–10/F2–10) mouse model for hereditary breast cancer, we have previously stud...

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Main Authors: Pajic, Marina, Kersbergen, Ariena, van Diepen, Frank, Pfauth, Anita, Jonkers, Jos, Borst, Piet, Rottenberg, Sven
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2010
Assuntos:
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047802/
https://ncbi.nlm.nih.gov/pubmed/20855963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.18.13002
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