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The same beta-globin gene mutation is present on nine different beta-thalassemia chromosomes in a Sardinian population.
The predominant beta-thalassemia in Sardinia is the beta 0 type in which no beta-globin chains are synthesized in the homozygous state. We determined the beta-thalassemia mutations in this population by the oligonucleotide-probe method and defined the chromosome haplotypes on which the mutation resi...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1987
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033668/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2882 |
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