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A segment of GCN4 mRNA containing the upstream AUG codons confers translational control upon a heterologous yeast transcript.
GCN4 encodes a transcriptional activator in Saccharomyces cerevisiae that is regulated at the translational level. We show that an approximately 240-nucleotide segment from the GCN4 mRNA leader containing four AUG codons is sufficient to confer translational control typical of GCN4 upon a GAL1-lacZ...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1987
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3554249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2863 |
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