A segment of GCN4 mRNA containing the upstream AUG codons confers translational control upon a heterologous yeast transcript.

GCN4 encodes a transcriptional activator in Saccharomyces cerevisiae that is regulated at the translational level. We show that an approximately 240-nucleotide segment from the GCN4 mRNA leader containing four AUG codons is sufficient to confer translational control typical of GCN4 upon a GAL1-lacZ...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Mueller, P P, Harashima, S, Hinnebusch, A G
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1987
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3554249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2863
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