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Cooling-Sensitive TRPM8 Is Thermostat of Skin Temperature against Cooling

We have shown that cutaneous cooling-sensitive receptors can work as thermostats of skin temperature against cooling. However, molecule of the thermostat is not known. Here, we studied whether cooling-sensitive TRPM8 channels act as thermostats. TRPM8 in HEK293 cells generated output (y) when temper...

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Autors principals: Tajino, Koji, Hosokawa, Hiroshi, Maegawa, Shingo, Matsumura, Kiyoshi, Dhaka, Ajay, Kobayashi, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047576/
https://ncbi.nlm.nih.gov/pubmed/21407809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017504
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