Prognostic effect of epidermal growth factor receptor gene mutations and the aberrant phosphorylation of Akt and ERK in ovarian cancer

OBJECTIVES: We herein assessed the influence of Epidermal Growth Factor Receptor (EGFR) gene mutations on EGFR expression levels, downstream mediators such as Akt or ERK and overall survival in patients with ovarian cancer. RESULTS: Twenty-nine EGFR gene mutations were detected in 24 of 102 patinets...

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Detalhes bibliográficos
Main Authors: Tanaka, Yoshimichi, Terai, Yoshito, Tanabe, Akiko, Sasaki, Hiroshi, Sekijima, Tatsuharu, Fujiwara, Satoe, Yamashita, Yoshiki, Kanemura, Masanori, Ueda, Masatsugu, Sugita, Michio, Franklin, Wilbur A, Ohmichi, Masahide
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047101/
https://ncbi.nlm.nih.gov/pubmed/21057220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.1.13877
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