The induction of S100p expression by the Prostaglandin E(2) (PGE(2))/EP4 receptor signaling pathway in colon cancer cells

BACKGROUND: Prostaglandin E(2) (PGE(2)) levels are frequently elevated in colorectal carcinomas. PGE(2) is perceived via four transmembrane G protein coupled receptors (EP1-4), among which the EP4 receptor is most relevant. PGE(2)/EP4-receptor interaction activates CREB via the ERK/MEK pathway. Howe...

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Detalles Bibliográficos
Autores principales: Chandramouli, Anupama, Mercado-Pimentel, Melania E, Hutchinson, Anthony, Gibadulinová, Adriana, Olson, Erik R, Dickinson, Sally, Shañas, Reneé, Davenport, Jennifer, Owens, Janae, Bhattacharyya, Achyut K, Regan, John W, Pastorekova, Silvia, Arumugam, Thiruvengadam, Logsdon, Craig D, Nelson, Mark A
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2010
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047097/
https://ncbi.nlm.nih.gov/pubmed/20890108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.10.13373
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