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Effects of DNA supercoiling on the topological properties of nucleosomes.

In the nucleosome core particle, at least 145 base pairs of DNA are bound to the histone octamer in a superhelical conformation. We have asked what effect the presence of these particles has on the ability of DNA gyrase to supercoil DNA. Synthetic minichromosomes, constructed by reconstituting compl...

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Bibliografiske detaljer
Main Authors: Garner, M M, Felsenfeld, G, O'Dea, M H, Gellert, M
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC304709/
https://ncbi.nlm.nih.gov/pubmed/3033656
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