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Development of Second-Generation VEGFR Tyrosine Kinase Inhibitors: Current Status

The vascular endothelial growth factor (VEGF) signaling pathway appears to be the dominant pathway involved in tumor angiogenesis, providing a rationale for targeting the VEGF receptors (VEGFR-1, -2, and -3) in the treatment of cancers. In particular, VEGF signaling is thought to be important in ren...

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Detalhes bibliográficos
Main Authors: Bhargava, Pankaj, Robinson, Murray O.
Formato: Artigo
Idioma:Inglês
Publicado em: Current Science Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047052/
https://ncbi.nlm.nih.gov/pubmed/21318618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-011-0154-3
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