Systemic Delivery of Liposome-Incorporated Adrenomedullin Receptor (ADMR) Small Interfering RNA Against Tumor and Its Microenvironment Reduced Pancreatic Tumor Growth

BACKGROUND: Pancreatic cancer is a major oncologic challenge due to its aggressive growth and metastasis. Our previous study showed that adrenomedullin (AM) is highly expressed in pancreatic cancer and stimulates pancreatic cancer cells leading to increased tumor growth and metastasis.(1) The curren...

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Main Authors: Ramachandran, Vijaya, Arumugam, Thiruvengadam, Langley, Robert, Hwang, Rosa F., Vivas-Mejia, Pablo, Sood, Anil K., Lopez-Berestein, Gabriel, Logsdon, Craig D.
Formato: Artigo
Idioma:Inglês
Publicado em: International Society of Gastrointestinal Oncology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047045/
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