Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins.
The hypothesis that cellular protein carboxyl-methylation reactions recognize altered aspartyl residues as part of a protein repair pathway has been tested in an in vitro system using tetragastrin (Trp-Met-Asp-Phe-NH2) as a model sequence. The L-isoaspartyl form of tetragastrin, where the phenylalan...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1987
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304704/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472227/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2595 |
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