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Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins.

The hypothesis that cellular protein carboxyl-methylation reactions recognize altered aspartyl residues as part of a protein repair pathway has been tested in an in vitro system using tetragastrin (Trp-Met-Asp-Phe-NH2) as a model sequence. The L-isoaspartyl form of tetragastrin, where the phenylalan...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: McFadden, P N, Clarke, S
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1987
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3472227/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.9.2595
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