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The PI3K p110δ Regulates Expression of CD38 on Regulatory T Cells

The PI3K pathway has emerged as a key regulator of regulatory T cell (Treg) development and homeostasis and is required for full Treg-mediated suppression. To identify new genes involved in PI3K-dependent suppression, we compared the transcriptome of WT and p110δ(D910A) Tregs. Among the genes that w...

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Auteurs principaux: Patton, Daniel T., Wilson, Marcus D., Rowan, Wendy C., Soond, Dalya R., Okkenhaug, Klaus
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046981/
https://ncbi.nlm.nih.gov/pubmed/21390257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017359
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