Activation of Peroxisome Proliferator–Activated Receptor δ Inhibits Streptozotocin-Induced Diabetic Nephropathy Through Anti-Inflammatory Mechanisms in Mice

OBJECTIVE: Activation of the nuclear hormone receptor peroxisome proliferator–activated receptor (PPAR)-δ has been shown to improve insulin resistance, adiposity, and plasma HDL levels. Several studies have reported that activation of PPARδ is atheroprotective; however, the role of PPARδ in renal fu...

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Bibliografiske detaljer
Main Authors: Matsushita, Yuichi, Ogawa, Daisuke, Wada, Jun, Yamamoto, Noriko, Shikata, Kenichi, Sato, Chikage, Tachibana, Hiromi, Toyota, Noriko, Makino, Hirofumi
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2011
Fag:
Complications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046857/
https://ncbi.nlm.nih.gov/pubmed/21270242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1361
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