Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice: Control of Islet Vasculature and Vascular Endothelial Growth Factor by Glucose

OBJECTIVE: β-Cell and islet endothelial cell destruction occurs during the progression of type 1 diabetes, but, paradoxically, β-cell proliferation is increased during this period. Altered glucose tolerance may affect β-cell mass and its association with endothelial cells. Our objective was to study...

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Detalhes bibliográficos
Main Authors: Akirav, Eitan M., Baquero, Maria-Teresa, Opare-Addo, Lynn W., Akirav, Michael, Galvan, Eva, Kushner, Jake A., Rimm, David L., Herold, Kevan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046848/
https://ncbi.nlm.nih.gov/pubmed/21307078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0793
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