Increased Expression of Macrophage-Inducible C-type Lectin in Adipose Tissue of Obese Mice and Humans

OBJECTIVE: We have provided evidence that saturated fatty acids, which are released from adipocytes via macrophage-induced adipocyte lipolysis, serve as a naturally occurring ligand for the Toll-like receptor (TLR) 4 complex in macrophages, thereby aggravating obesity-induced adipose tissue inflamma...

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Auteurs principaux: Ichioka, Masayuki, Suganami, Takayoshi, Tsuda, Naoto, Shirakawa, Ibuki, Hirata, Yoichiro, Satoh-Asahara, Noriko, Shimoda, Yuri, Tanaka, Miyako, Kim-Saijo, Misa, Miyamoto, Yoshihiro, Kamei, Yasutomi, Sata, Masataka, Ogawa, Yoshihiro
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2011
Sujets:
Obesity Studies
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046842/
https://ncbi.nlm.nih.gov/pubmed/21282371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0864
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