Human Blood CXCR5(+)CD4(+) T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

Although a fraction of human blood memory CD4(+) T cells expresses chemokine (C-X-C motif) receptor 5 (CXCR5), their relationship to T follicular helper (Tfh) cells is not well-established. Here we show that human blood CXCR5(+) CD4(+) T cells share functional properties with Tfh cells, and appear t...

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Detalhes bibliográficos
Main Authors: Morita, Rimpei, Schmitt, Nathalie, Bentebibel, Salah-Eddine, Ranganathan, Rajaram, Bourdery, Laure, Zurawski, Gerard, Foucat, Emile, Dullaers, Melissa, Oh, SangKon, Sabzghabaei, Natalie, Lavecchio, Elizabeth M, Punaro, Marilynn, Pascual, Virginia, Banchereau, Jacques, Ueno, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046815/
https://ncbi.nlm.nih.gov/pubmed/21215658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.12.012
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