Complete nucleotide sequence of an attenuated hepatitis A virus: comparison with wild-type virus.

The complete nucleotide sequence of an attenuated hepatitis A virus, HAV HM-175/7 MK-5, was determined from cloned cDNA. This virus was derived from wild-type HAV HM-175 after 32 passages in African green monkey kidney cells. The resultant cell culture-adapted virus is attenuated for chimpanzees. Th...

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Bibliografiske detaljer
Main Authors: Cohen, J I, Rosenblum, B, Ticehurst, J R, Daemer, R J, Feinstone, S M, Purcell, R H
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC304679/
https://ncbi.nlm.nih.gov/pubmed/3031686
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